Lassa Fever: Oyo Confirms Five Cases, One Death Recorded

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Oyo State Governor- Engr Seyi Makinde

The Oyo State Government has confirmed the detection of five cases of Lassa fever within its borders, with one of the infected persons sadly losing her life. Health authorities say the development has triggered an immediate escalation of public health response efforts, especially as Nigeria continues to battle a challenging Lassa fever season marked by rising infections and an unusually high fatality rate.

The confirmation was made public through the Oyo State Ministry of Health, with the Commissioner for Health, Dr. Oluwaserimi Ajetunmobi, explaining that emergency response systems have already been activated to contain any possible spread of the disease. According to the ministry, the situation is being closely monitored in collaboration with national health agencies, while surveillance has been intensified across all local government areas in the state.

The confirmed cases were identified after laboratory investigations carried out on suspected patients returned positive results for the Lassa virus. One of the most critical cases involved a 44-year-old woman who had been receiving treatment at the University College Hospital in Ibadan. Despite efforts by medical personnel to stabilize her condition, she passed away on April 11, 2026. Subsequent laboratory confirmation, which established that she had been infected with the Lassa virus, was received two days later on April 13, prompting swift public health action from the state government.

Health officials have since moved quickly to trace individuals who may have come into contact with the deceased or other confirmed patients. Contact tracing teams have been deployed across affected communities, with a focus on identifying, monitoring, and managing anyone who may have been exposed to the virus during the infectious period.

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Dr. Ajetunmobi stated that the state government is treating the situation with the highest level of seriousness, noting that containment remains the priority at this stage. She emphasized that all necessary emergency mechanisms have been activated, including surveillance systems designed to detect new cases early and prevent further transmission within communities.

The Ministry of Health also confirmed that all 33 local government areas in Oyo State have been placed on heightened alert. Health workers in both urban and rural areas have been instructed to increase monitoring activities, particularly in densely populated communities and border towns where movement of people may increase the risk of spread. Hospitals and primary healthcare centers have also been advised to strengthen infection prevention protocols and immediately report any suspected cases showing symptoms consistent with Lassa fever.

In addition to surveillance and contact tracing, the state government has reinforced the importance of safe burial practices. Officials explained that Lassa fever can still be transmitted from the body of a deceased infected person if proper precautions are not taken. As a result, specialized teams have been deployed to ensure that burial procedures are carried out safely and in line with national infection control guidelines. Families affected by suspected or confirmed cases are being sensitized on the importance of allowing trained health personnel to handle such burials to reduce risk to the wider community.

While the situation in Oyo State has drawn attention, health authorities say it is part of a wider national public health challenge. Across Nigeria, Lassa fever has continued to pose a serious concern, particularly during peak transmission periods. According to data from the Nigeria Centre for Disease Control, the 2026 outbreak season has recorded a noticeable rise in both confirmed cases and fatalities compared to the previous year.

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University College Hospital, Ibadan

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Reports indicate that Nigeria has recorded thousands of suspected infections so far this year, with several hundred cases confirmed through laboratory testing. The number of deaths has also increased significantly, contributing to a case fatality rate that health experts describe as worrying. The national case fatality rate currently stands at over 25 percent, which is higher than what was recorded in the same period last year. This means that more than one in every four confirmed patients has not survived the infection, highlighting ongoing challenges in early detection, access to treatment, and timely presentation at health facilities.

Several states have remained persistent hotspots for the disease, including Ondo, Edo, Bauchi, and Taraba. However, the emergence of confirmed cases in Oyo State signals a continued geographical spread that underscores the need for sustained vigilance across all regions of the country, including the southwest.

Health experts have noted that Lassa fever is endemic in Nigeria, meaning it occurs regularly in certain parts of the country, particularly during dry seasons when rodent activity tends to increase. The disease is primarily transmitted through contact with food or household items contaminated by urine or feces of infected multimammate rats, which are commonly found in many communities. Human-to-human transmission can also occur, especially in healthcare settings where proper infection control measures are not strictly followed.

Understanding the symptoms of Lassa fever is critical for early detection and treatment. The illness often begins with non specific signs that can easily be mistaken for malaria or other common infections. Patients may experience fever, general weakness, sore throat, muscle pain, headaches, and fatigue. As the disease progresses, more severe symptoms may develop, including vomiting, diarrhea, chest pain, facial swelling, and in extreme cases, bleeding from the nose, mouth, or other body openings. These severe manifestations typically indicate advanced infection and require urgent medical attention.

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Medical professionals emphasize that early presentation at a healthcare facility significantly improves the chances of survival. Antiviral treatment is available and most effective when administered in the early stages of the disease. However, delays in seeking care remain a major factor contributing to high mortality rates in many communities.

In response to the growing number of cases nationwide, health authorities have intensified public awareness campaigns, urging citizens to adopt preventive measures that reduce contact with rodents. These include ensuring that homes are properly sealed to prevent rats from entering living spaces, storing food items in secure containers, and maintaining clean environments free of waste that may attract rodents.

Residents are also advised to avoid drying food items such as grains, garri, or other agricultural products in open spaces where they may be exposed to contamination. Proper waste disposal practices are being encouraged, with emphasis on keeping refuse away from residential areas to discourage rodent infestation. Good hygiene practices, including regular hand washing and cleaning of food storage areas, are also being highlighted as essential preventive steps.

The Oyo State Government has appealed to residents not to panic but to remain calm and vigilant. Officials stress that Lassa fever is both preventable and treatable, particularly when detected early and managed in properly equipped health facilities. They also reiterated that the government is fully committed to supporting healthcare institutions with the resources needed to manage cases effectively and reduce the risk of further spread.

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Dr. Ajetunmobi further urged anyone experiencing persistent fever or related symptoms to seek immediate medical attention rather than resorting to self medication or traditional remedies. She explained that early diagnosis remains one of the most powerful tools in reducing fatalities associated with the disease.

As surveillance efforts continue across Oyo State, health teams remain on alert for any new developments. Authorities say the coming weeks will be crucial in determining whether the current situation can be contained effectively or whether additional cases will emerge. For now, the focus remains on containment, public education, and ensuring that healthcare systems are adequately prepared to respond.

The state government has reaffirmed its commitment to protecting public health and working closely with national agencies to ensure that the outbreak does not escalate further. Residents are encouraged to stay informed through official channels and cooperate fully with health workers engaged in contact tracing and community monitoring activities.

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